Pediatricsintermediate

Arrange the following steps in the pathophysiologic progression from acute pericarditis to cardiac tamponade in the correct chronological order.

Answer

Development of acute pericardial inflammation, Accumulation of fluid in the pericardial space, Elevation of intrapericardial pressure beyond reserve volume, Impairment of diastolic cardiac filling

Explanation

The appropriate sequence begins with **pericardial inflammation**, which can lead to accumulation of fluid in the pericardial space. As the volume increases, pressure initially rises slowly, but after a critical point it can rise rapidly. Sufficient pressure then interferes with cardiac filling and may produce tamponade. This ordering describes a possible progression, not an inevitable outcome of every episode of acute pericarditis. **Key takeaway:** An effusion becomes dangerous when pressure within the pericardial space impairs cardiac filling. **Glossary:** **Pericardial pressure**: pressure exerted by contents of the pericardial space. **Cardiac filling**: blood entering the heart chambers, particularly during diastole.

Related Questions

Want to practice more questions like this?

Join myBenkio free and practice past questions for your Nigerian university courses with AI explanations for every answer.

Start Practicing Free