Arrange the general steps of endocrine signaling in chronological order, from initial signal release to the cellular outcome.

Answer

An endocrine cell secretes a hormone, The hormone travels through the bloodstream to distant tissues, The hormone binds to a specific receptor on or in a target cell, The target cell alters its physiological activity

Explanation

The sequence begins with **secretion** by a specific cell, followed by **transport** to the destination. The hormone then binds a receptor on a target cell, where it can alter enzyme activity, membrane movement, or gene expression. This ordering captures the basic signaling path rather than a single hormone-specific pathway.\n\n**Key takeaway:** Secretion precedes transport, receptor binding, and the target-cell response.\n\n**Glossary:** **Secretion**: Release of a substance from a cell; **receptor binding**: Association of a signal with its target molecule.

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