In the pathogenesis of infective endocarditis, mechanical injury from turbulent blood flow exposes subendothelial collagen, leading to the formation of a sterile platelet-fibrin nidus known as nonbacterial thrombotic ________.
Answer
endocarditis
Explanation
The lecture describes **erosion** at sites of turbulent flow as the location where vegetations usually develop. **Key takeaway:** Flow-related tissue injury helps explain risk in certain congenital lesions. **Glossary:** Intima: the inner layer of a blood vessel.