BCH101intermediate
How many chiral centers are present in the open-chain form of fructose?
Answer
Three
Explanation
### Why this is right
Open-chain fructose is a six-carbon ketose. Its carbonyl carbon and terminal carbon atoms are not chiral, leaving three internal carbons with four different substituents.
### The other options
- **Two**: this misses one stereogenic carbon in the open-chain structure.
- **Four**: this incorrectly counts a carbonyl carbon or a terminal carbon as chiral.
- **One**: this counts too few of the stereogenic centers.
### Terms
- **Ketose**: a sugar containing a ketone carbonyl group.
- **Chiral center**: an atom, usually carbon, attached to four different substituents.
### Remember
For open-chain sugars, count the tetrahedral carbons with four different attachments.
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