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Select ALL statements about prostaglandin ripening supported by the material:

Answer

Prostaglandins can ripen the cervix and stimulate uterine contractions, Their cervical and contraction-stimulating effects cannot easily be separated, They can increase uterine hyperstimulation with fetal heart-rate changes

Explanation

Synthetic prostaglandins may both ripen the cervix and stimulate uterine contractions; the slides note that these effects cannot easily be separated. They can reduce the likelihood of not delivering within 24 hours and reduce caesarean requirement, but increase the risk of uterine hyperstimulation with fetal heart-rate changes. They do not remove the need for monitoring. **Key takeaway:** Prostaglandin efficacy must be balanced against hyperstimulation and fetal heart-rate risk. **Glossary:** **Hyperstimulation**: excessive uterine activity associated with an abnormal fetal heart-rate pattern. **FHR**: fetal heart rate.

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