Match each diagnostic modality used in hypertrophic cardiomyopathy (HCM) with its corresponding clinical utility or finding:
Diagnostic Modalities:
1. Electrocardiogram (ECG)
2. Echocardiography
3. Doppler flow study
Clinical Findings:
A. Identifies asymmetric, concentric, or apical patterns of left ventricular hypertrophy (LVH)
B. May demonstrate signs of LVH before structural wall thickening is visible on imaging
C. Can detect diastolic dysfunction before overt ventricular hypertrophy develops
Answer
1-B, 2-A, 3-C
Explanation
The slides describe ECG evidence of **left ventricular hypertrophy (LVH)** that may predate echocardiographic findings. Echocardiography can reveal asymmetric, concentric, or apical hypertrophy. Doppler studies may detect diastolic dysfunction before visible hypertrophy develops. These findings illustrate why more than one diagnostic modality may be useful. **Key takeaway:** ECG, echo, and Doppler provide complementary information in HCM.\n\n**Glossary:** **LVH**: Left ventricular hypertrophy. **Doppler**: Ultrasound assessment of blood-flow characteristics.