Paedbasic
Arrange the events in the pathogenesis of tetanus in chronological order, from initial exposure to disease outcome.
Answer
Clostridium tetani enters the body through a wound, Tetanospasmin toxin is produced, Clinical manifestations of tetanus develop
Explanation
The sequence starts with entry of the organism, followed by toxin production and then clinical manifestations. This is a simplified disease sequence; the detailed steps of wound germination and toxin action are covered in the pathogenesis concept. **Key takeaway:** Tetanus manifestations follow toxin production after organism entry.\n\n**Glossary:** **Manifestation**: a sign or symptom of a disease.
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