Pediatricsintermediate
Explain how turbulent flow in congenital heart disease can predispose to infective endocarditis.
Answer
High-velocity flow through a defect or stenotic orifice can injure the endocardial or intimal surface. Vegetations may then form at the site of erosion when microorganisms seed the damaged area.
Explanation
The lecture links high-velocity turbulent flow to endocardial or intimal erosion and identifies this damaged site as a location where vegetations form. **Key takeaway:** Endothelial injury creates a substrate for vegetation development. **Glossary:** Vegetation: an infected mass associated with the endocardial surface; stenotic: abnormally narrowed.
Related Questions
- Which factors are associated with higher ARF occurrence or susceptibility? Select ALL that apply.(intermediate)
- Explain why ARF remains an important public-health problem despite declining incidence in many industrialized countries.(intermediate)
- Acute rheumatic fever occurs most frequently in children and adolescents aged 5 to 15 years.(basic)
- After a prior episode of ARF, recurrence following untreated GAS pharyngitis can approach 50%.(intermediate)
- The highest incidence of ARF occurs in children aged approximately _____ years.(basic)
Want to practice more questions like this?
Join myBenkio free and practice past questions for your Nigerian university courses with AI explanations for every answer.
Start Practicing Free