Pediatricsadvanced
Compare the transient forms of HCM described in infants of diabetic mothers and premature infants receiving corticosteroids.
Answer
Infants of diabetic mothers may have transient HCM, with or without left ventricular outflow tract obstruction; increased LV mass usually regresses within several months. Premature infants receiving corticosteroids for chronic lung disease may also develop transient HCM, which usually resolves rapidly after corticosteroid cessation.
Explanation
Both situations are described as **transient forms** of myocardial hypertrophy, but their contexts and resolution timelines differ. In infants of diabetic mothers, increased LV mass usually regresses over several months. In premature infants receiving corticosteroids for chronic lung disease, the condition usually resolves rapidly after the steroid is stopped. **Key takeaway:** Identify the associated context and expected course before assuming persistent primary HCM.\n\n**Glossary:** **LV mass**: The mass of the left ventricular muscle. **Outflow tract obstruction**: Impeded blood flow leaving the ventricle.
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