Bchbasic
Under anaerobic conditions, lactate dehydrogenase uses reduced nicotinamide adenine dinucleotide (NADH) to reduce pyruvate and regenerate nicotinamide adenine dinucleotide (NAD+).
Answer
true
Explanation
### Why this is right
Lactate dehydrogenase transfers reducing equivalents from NADH to pyruvate, producing lactate and NAD+. The regenerated NAD+ is needed for the oxidation step of glycolysis.
### The concept
Anaerobic conversion to lactate does not itself produce the glycolytic ATP. Its key role is to recycle NAD+, allowing glycolysis to continue when the respiratory chain cannot reoxidize NADH quickly enough.
### Terms
- **NADH**: Reduced nicotinamide adenine dinucleotide, an electron carrier.
- **NAD+**: Oxidized nicotinamide adenine dinucleotide.
- **Lactate dehydrogenase**: The enzyme that interconverts pyruvate and lactate.
### Remember
Lactate formation regenerates NAD+ for glycolysis.
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