Bchbasic
Which enzyme cleaves fructose-1-phosphate into glyceraldehyde and dihydroxyacetone phosphate?
Answer
Aldolase B
Explanation
### Why this is right
In the liver fructose pathway, fructokinase forms fructose-1-phosphate, and aldolase B cleaves it into glyceraldehyde and dihydroxyacetone phosphate. These products can enter intermediary metabolism.
### The concept
Fructose can also be phosphorylated by hexokinase to fructose-6-phosphate, which enters glycolysis by a different route. Aldolase B is specifically associated with the fructose-1-phosphate pathway.
### The other options
- **Galactokinase**: Phosphorylates galactose, not fructose-1-phosphate.
- **Hexokinase**: Can form fructose-6-phosphate from fructose but does not cleave fructose-1-phosphate.
- **Lactase**: Hydrolyzes lactose into glucose and galactose.
### Terms
- **Dihydroxyacetone phosphate**: A three-carbon glycolytic intermediate.
- **Aldolase B**: The enzyme that cleaves fructose-1-phosphate in liver fructose metabolism.
### Remember
Aldolase B deficiency is associated with hereditary fructose intolerance.
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