Bchintermediate
Match each enzyme with its gluconeogenic role.
Answer
Pyruvate carboxylase - Pyruvate to oxaloacetate, Phosphoenolpyruvate carboxykinase - Oxaloacetate to phosphoenolpyruvate, Fructose-1,6-bisphosphatase - Fructose-1,6-bisphosphate to fructose-6-phosphate, Glucose-6-phosphatase - Glucose-6-phosphate to glucose
Explanation
### The pairs
| Item | Matches | Why |
|---|---|---|
| Pyruvate carboxylase | Pyruvate to oxaloacetate | This enzyme adds carbon dioxide to pyruvate and uses adenosine triphosphate. |
| Phosphoenolpyruvate carboxykinase | Oxaloacetate to phosphoenolpyruvate | It uses guanosine triphosphate and releases carbon dioxide. |
| Fructose-1,6-bisphosphatase | Fructose-1,6-bisphosphate to fructose-6-phosphate | Hydrolysis bypasses the phosphofructokinase reaction. |
| Glucose-6-phosphatase | Glucose-6-phosphate to glucose | It enables free glucose production in tissues that express it. |
### Terms
- **Oxaloacetate**: A four-carbon intermediate in the tricarboxylic acid cycle and gluconeogenesis.
- **Carboxykinase**: An enzyme that couples decarboxylation to phosphate transfer.
### Remember
Track the substrate and product to identify each bypass enzyme.
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