Bchbasic
Which molecule donates activated glucose units during glycogen synthesis?
Answer
Uridine diphosphate glucose (UDP-glucose)
Explanation
### Why this is right
Glycogen synthase transfers glucose from UDP-glucose to a glycogen chain, releasing uridine diphosphate. UDP-glucose is the activated glucose donor used in glycogen synthesis.
### The concept
Glucose is first converted to glucose-1-phosphate, which reacts with uridine triphosphate to produce UDP-glucose. The activated sugar is then incorporated into glycogen.
### The other options
- **Glucose-6-phosphate**: It is an intermediate that can be converted to glucose-1-phosphate, but it is not the direct donor to glycogen synthase.
- **ATP**: It supplies energy in other reactions but does not donate glucose units.
- **Fructose-1,6-bisphosphate**: This is a glycolytic intermediate, not a glycogen precursor donor.
### Terms
- **UDP-glucose**: Activated glucose linked to uridine diphosphate.
- **Glycogen synthase**: The enzyme that lengthens glycogen chains.
### Remember
Glycogen synthase uses activated UDP-glucose, not free glucose.
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