Bchintermediate
High adenosine triphosphate (ATP) concentration stimulates isocitrate dehydrogenase, while adenosine monophosphate (AMP) inhibits it.
Answer
false
Explanation
### Why this is right
The statement reverses the regulation described in the material. High ATP decreases isocitrate dehydrogenase activity, while AMP stimulates the reaction.
### The concept
This regulation links cycle activity to cellular energy status. ATP signals abundant energy and restrains oxidation; AMP signals lower energy availability and promotes the reaction.
### Terms
- **ATP**: Adenosine triphosphate, a high-energy cellular nucleotide.
- **AMP**: Adenosine monophosphate, a lower-energy nucleotide that can signal energy demand.
- **Isocitrate dehydrogenase**: A regulated enzyme that oxidizes isocitrate in the cycle.
### Remember
High energy slows this cycle control point; AMP activates it.
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