Bchbasic
The inherited deficiency of galactose-1-phosphate uridyltransferase causes _____.
Answer
galactosemia
Explanation
### Why this is right
Classic galactosemia is associated with inherited deficiency of galactose-1-phosphate uridyltransferase. Galactose and galactose-1-phosphate can accumulate, especially after ingestion of galactose or lactose.
### The concept
The transferase normally converts galactose-1-phosphate and UDP-glucose into UDP-galactose and glucose-1-phosphate. Blocking this step prevents normal galactose metabolism.
### Terms
- **Galactosemia**: An inherited disorder of galactose metabolism.
- **Galactose-1-phosphate**: A phosphorylated galactose intermediate.
### Remember
Galactose-1-phosphate uridyltransferase deficiency identifies classic galactosemia.
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